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Ketones

This test analyses the levels of ketones in your urine to see whether you are in a state of nutritional ketosis when following a ketogenic diet.  Ketones are produced when carbohydrate intake is restricted, and fats and proteins are broken down to supply cellular energy instead.  Without glucose from carbohydrates, the body needs to find alternative forms of fuel and uses up fats and proteins in a process called ketosis.


Low-carbohydrate-ketogenic diets (LCKD) have been shown to help reduce appetite, improve insulin resistance, and optimise blood sugar balance, which in turn can support healthy weight balance and optimal health.  There are many versions of low-carb-ketogenic diets with varying amounts of carbohydrates recommended, though it is generally agreed that <20-50g of carbohydrate is consumed per day on a typical LCKD.  This pushes the body to use fats and proteins for fuel instead.  It can take several weeks to adapt to a ketogenic diet and to get used to being in nutritional ketosis, and it is important to keep monitoring the balance of your meals and your ketone levels. 

References

Bono M.J., Reygaert W.C., Urinary Tract Infection.  In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: <https://www.ncbi.nlm.nih.gov/books/NBK470195/> [Accessed 13th June 2020]

Foley K.F., Boccuzzi L., 2010. Urine Calcium: Laboratory Measurement and Clinical Utility, Laboratory Medicine [online] vol41 (11) 683–686 doi.org/10.1309/LM9SO94ZNBHEDNTM

Frassetto L, Banerjee T, Powe N, Sebastian A., 2018.  Acid Balance, Dietary Acid Load, and Bone Effects-A Controversial Subject. Nutrients [online] vol10(4) 517. doi:10.3390/nu10040517


Gershuni, V.M., Yan, S.L. & Medici, V. 2018. Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome. Current Nutrition Reports [online]7, 97–106 doi.org/10.1007/s13668-018-0235-0

Gropper, S.S., Smith, J., Groff, J.L. 2005 Advanced Nutrition and Human Metabolism 4th ed. Belmont: Thomson Wadsworth

Jacob, R.A., Sotoudeh, G., 2002. Vitamin C function and status in chronic disease. Nutrition in Clinical Care [online] vol5(2) 66‐74. doi:10.1046/j.1523-5408.2002.00005.x

King, G., Beins, M., Larkin, J. Summers B., Ordman A.B., 1994. Rate of excretion of vitamin C in human urine. AGE [online] 17, 87–92 doi.org/10.1007/BF02435011

Logan-Sprenger H.M., Spriet L. L., 2013. The Acute Effects of Fluid Intake on Urine Specific Gravity and Fluid Retention in a Mildly Dehydrated State Journal of Strength and Conditioning Research [online] Vol27 Iss. 4 1002-1008 doi: 10.1519/JSC.0b013e31826052c7

NHS UK, 2011. Six to Eight Glasses of Water Still Best [online] Available at www.nhs.uk/news/food-and-diet/six-to-eight-glasses-of-water-still-best/ [Accessed online 07/12/2020]

Nikolac Gabaj, N., Miler, M., Unic, A., Milevoj Kopcinovic, L., Vrtaric, A., & Culej, J. 2020. Ascorbic acid in urine still compromises urinalysis results. Annals of Clinical Biochemistry [online] vol57(1), 64–68. doi.org/10.1177/0004563219882051

 

Osuna-Padilla I.A., Leal-Escobar G., Garza-García C.A., Rodríguez-Castellanos F.E., 2019. Dietary load: Mechanisms and evidence of its health repercussions Nefrologia (English edition) vol 39: 343-354 doi.org/10.1016/j.nefro.2018.10.005.

Park, S. M., Jee, J., Joung, J. Y., Cho, Y. Y., Sohn, S. Y., Jin, S. M., Hur, K. Y., Kim, J. H., Kim, S. W., Chung, J. H., Lee, M. K., & Min, Y. K., 2014. High Dietary Sodium Intake Assessed by 24-hour Urine Specimen Increase Urinary Calcium Excretion and Bone Resorption Marker Journal of bone metabolism [online] vol21(3) 189–194. doi.org/10.11005/jbm.2014.21.3.189

Waugh, A., Grant, A. 2006. Ross and Wilson Anatomy and Physiology in Health and Illness Philadelphia: Churchill Livingstone

Welch A.A., Mulligan A., Bingham S.A., Khaw K., 2008. Urine pH is an indicator of dietary acid–base load, fruit and vegetables and meat intakes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk population study British Journal of Nutrition [e-journal] vol 99 iss.6 1335-1343 doi.org/10.1017/S0007114507862350

Westman, E.D., Feinman, R.D., Mavropoulos, J.C., Vernon, M.C., Volek, J.S., Wortman, J.A., Yancy, W.S., Phinney, S.D. 2007. Low-carbohydrate nutrition and metabolism The American Journal of Clinical Nutrition vol86, iss.2, 276–284 doi.org/10.1093/ajcn/86.2.276